Finding the right candidates for clinical trial enrollment can be challenging. For many researchers, this process involves manually searching through electronic health records for patients that meet complex sets of inclusion and exclusion criteria. This can quickly become a labor intensive and tedious task, and can make it difficult for researchers to meet time-sensitive enrollment windows.

The good news is that VigiLanz Research speeds up this process. The technology integrates with live data inside a hospital’s EHR and applies intelligent rule sets – tailored specifically to a clinical trial’s unique protocols – to automatically search the hospital’s entire network and alert researchers whenever an eligible candidate is identified.

Here are three of the top benefits hospitals are experiencing as a result of implementing this technology:

Benefit 1: Accelerate patient recruitment

VigiLanz Research makes finding patients for clinical trials in real time possible. Manual reviews only happen during work hours, but VigiLanz searches for qualified candidates 24/7. Once patients are identified, researchers can easily manage their eligibility status in a customizable worklist.

Benefit 2: Maximize the research team’s time

With less time needed for manual searches, researchers can focus on screening and enrolling more qualified candidates. This translates to significant time savings and frees up the team to focus on other high-value tasks, including the capacity to potentially participate in additional trials.

Benefit 3: Improve the likelihood of trial success

By screening all patients across every department in real time, VigiLanz Research helps ensure that every eligible patient who walks into the hospital is identified.This makes it easier for research teams to meet recruitment targets and time-sensitive enrollment windows.

See VigiLanz Research in action

Efficient patient recruitment for clinical trials has never been easier. Want to know more? Check out our recent case study with Sharp Grossmont Hospital to learn how they are using VigiLanz Research to streamline the recruitment process.

Customer Profile

Sharp HealthCare, a not-for-profit health system based in San Diego, is made up of four acute-care hospitals, three specialty hospitals, three affiliated medical groups, and a full spectrum of other facilities and services. Sharp Grossmont Hospital, the largest healthcare facility in East San Diego County with 536 beds, is known for outstanding programs in emergency and critical care, cardiac care, orthopedics, rehabilitation, neurology, women’s health, children’s health and hospice care.

Challenge

Sharp Grossmont Hospital is dedicated to expanding scientific knowledge and supporting medical advancements by serving as a clinical trial site. However, recruiting and enrolling patients in clinical trials is a challenging, labor-intensive, and time-consuming process. Industry research suggests that 11% of clinical trials never enroll a patient and 68% of sites fail to meet enrollment targets. When Sharp Grossmont Hospital began participating in a complex clinical trial in early 2020, it quickly became apparent that they were going to face similar challenges.

The trial was designed to evaluate the safety and efficacy of a new drug to reduce the risk of major cardiovascular events in patients with acute coronary syndrome and had a complex protocol that made clinical trial enrollment extremely difficult. Sharp Grossmont Hospital’s clinical research team, who at the time relied on a manual review process to identify eligible patients, found that the workflow was extremely inefficient.

“Screening for clinical trials with extensive and specific inclusion and exclusion criteria is very time-consuming,” said DeAnn Cary, PhD, Director of Research at Sharp HealthCare. “Manually screening for a trial like ours means casting a wide net to find potential subjects since they can be in multiple areas of the hospital.”

Solution

Sharp Grossmont Hospital knew there had to be a better way to approach clinical trial enrollment, and in 2020, partnered with VigiLanz to explore an alternative model. VigiLanz Research facilitates a more efficient recruitment process by continuously reviewing EHR data to find patients for clinical trials in real time.

Kyra Rashid, BS, MCR, Clinical Trial Specialist at Sharp, said the solution helps the organization identify eligible patients more quickly, including patients who might have otherwise been missed.

“The technology alerts our team as soon as eligible patients are identified, based on the study-specific inclusion and exclusion criteria,” she said. “It screens the entire hospital patient population, which saves us a significant amount of time that can then be reallocated to other initiatives.”

In addition to screening patients for the clinical trial, the solution provides:

A dynamic worklist that coordinators can use to view or modify patient eligibility status in real time
Automatic alerts that notify coordinators anytime an eligible candidate is located within the hospital network
Enterprise-level reporting that coordinators and leaders can use to evaluate study performance and easily evaluate potential clinical trials.

How VigiLanz Research Works

VigiLanz leverages study-specific inclusion and exclusion criteria to automatically review all patients across a hospital network.
VigiLanz screens the entire patient population to identify eligible patients in real time.
VigiLanz provides automated alerts and notifications to key team members when it identifies eligible patients.
Coordinators can track eligibility status, run timely reports, and manage the recruitment process in a customized worklist.

Outcomes

As a result of the VigiLanz Research partnership, Sharp Grossmont Hospital reduced the time needed to screen and enroll patients in the clinical trial. The time savings and workflow improvements also positively benefited the clinical research team.

“The coordinators’ time is now focused on a more narrowed pool of potential subjects, which allows more time to continue additional screening and accomplish more tasks in our day,” said Cary E. Murphy, BSN, CCRC, Clinical Trial Specialist at Sharp Healthcare. “This makes the team happier and more productive.”

Overall, the partnership:

Increased the number of patients screened. VigiLanz Research increased the number of patients screened to include all ED patients and all patients admitted in all 20 hospital departments.
Cut the time spent screening patients in half. The technology solution reduced the time needed to screen patients, freeing up the clinical research team to work on other high-value tasks.
Identified eligible patients faster. VigiLanz Research helped the team identify eligible patients in real time, which was vital to this time-sensitive study.

Another key benefit, Cary said, is the positive impact the new approach brings patients. “VigiLanz Research has improved our team’s efficiency and helped us ensure more eligible patients can participate in the trial. VigiLanz also helps ensure no potential study participant, regardless of department, is missed. As we work to advance drug and treatment development, we’re excited about how this approach will support those efforts.”

To learn more about how VigiLanz helps hospitals with efficient patient recruitment for clinical trials, visit https://vigilanzcorp.com/ today.

Related Resources: VigiLanz Research

Month: November 2022

Three Ways VigiLanz Supports Clinical Trial Recruitment